PrEP Well is an intervention funded by a 3-year California HIV/AIDS Research Program Implementation Science Award for Ending the HIV Epidemic in California. The PrEP Well program is a comprehensive implementation strategy that addresses structural barriers to HIV prevention for transgender and non-binary persons by integrating culturally appropriate and gender-affirming PrEP care into existing sexual and gender wellness

identify modifiable intervention targets for reducing substance use and intimate partner violence and strengthening engagement in the HIV care continuum during times of acute social and economic stress among young Black sexual minority men living with HIV in the US South.